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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Brevilin A Influence on STAT3 signalling Western Blot 12.50 µM A549R Homo sapiens
Brevilin A Influence on STAT3 signalling Western Blot 25.00 µM A549R Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 5.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 15.00 µM DU145 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 5.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 10.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on constitutive STAT3 activation Western Blot 15.00 µM MDA-MB-468 Homo sapiens
Brevilin A Influence on protein upon cytokine treatment Western Blot 10.00 µM HEK293T Homo sapiens
Brevilin A Influence on protein upon cytokine treatment Western Blot 10.00 µM Hela Homo sapiens
Brevilin A Influence on protein upon cytokine treatment Western Blot 10.00 µM HepG2 Homo sapiens
Brevilin A Influence on protein upon cytokine treatment RT-PCR 10.00 µM HEK293T Homo sapiens
Brevilin A Influence on protein upon cytokine treatment RT-PCR 10.00 µM Hela Homo sapiens
Brevilin A Influence on protein upon cytokine treatment RT-PCR 10.00 µM HepG2 Homo sapiens
Brevilin A Influence on JAK2-JH1 overexpressed protein Western Blot 10.00 µM HEK293T Homo sapiens
Brevilin A Influence on JAK2-JH1 overexpressed protein Western Blot 15.00 µM HEK293T Homo sapiens
Brevilin A Influence on c-Src overexpressed protein Western Blot 15.00 µM HEK293T Homo sapiens
Brevilin A Influence on protein overexpression Western Blot 15.00 µM HEK293T (JAK1-JH1) Homo sapiens
Brevilin A Influence on protein overexpression Western Blot 15.00 µM HEK293T (JAK2-JH1) Homo sapiens
Brevilin A Influence on protein overexpression Western Blot 15.00 µM HEK293T (JAK3-JH1) Homo sapiens
Brevilin A Influence on protein overexpression Western Blot 15.00 µM HEK293T (Tyk2-JH1) Homo sapiens
Brevilin A Influence on apoptosis Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on apoptosis Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on apoptosis Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on apoptosis Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on apoptosis Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on apoptosis Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on JAK2/STAT3 signalling in melanoma cells Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A2058 Homo sapiens